http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2449618-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff987fcc98c2a781f82b2f2165f478e4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate | 2006-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75f581a0bc4bdb51c7711c52731977ad |
publicationDate | 2014-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2449618-T3 |
titleOfInvention | Phenoxyacetic acids as activators of PPAR-delta |
abstract | A compound of formula IIb: ** Formula ** or a pharmaceutically acceptable salt thereof, in which: X is SCH2; X1 is O or S; R1 is H, C1-8 alkyl, heteroaryl or C3-10 cycloalkyl, in which each R1 group is substituted with 0-4 R1a; R1a, at each occurrence, is selected from C1-6 alkyl substituted with 0-3 R1b; C2-6 alkynyl substituted with 0-2 R1b; aryl substituted with 0-2 R1b, heteroaryl substituted with 0-2 R1b10, C3-10 cycloalkyl substituted with 0-2 R1b and a heterocycle substituted with 0-2 R1b; R1b, at each occurrence, is selected from OH substituted with 0-1 R1c; SH substituted with 0-1 R1c; Cl; F; NH2 substituted with 0-2 R1c; -CN; NO2; methanesulfonyl; C1-4 alkyl substituted with 0-3 R1c; C2-4 alkenyl substituted with 0-2 R1c; aryl substituted with 0-2 R1c; heteroaryl substituted with 0-2 R1c; C3-6 cycloalkyl substituted with 0-2 R16; and a heterocycle substituted with 0-2 R1c; R1c, at each occurrence, is selected from OH, SH, Cl, F, NH2, -CN, NO2, C1-4 alkyl and C2-4 alkenyl; aryl substituted with 0-2 R1d, heteroaryl substituted with 0-2 R1d, C3-6 cycloalkyl substituted with 0-2 R1d and heterocycle substituted with 0-2 R1d; R1d, at each occurrence, is selected from OH, SH, Cl, F, NH2, -CN, NO2, C1-4 alkyl; and C2-4 alkenyl; R2a is selected from Ch alkyl substituted with 0-2 R2b, aryl substituted with 0-2 R2b and heteroaryls substituted with 0-2 R2b; R2b, at each occurrence, is selected from OH substituted with 0-1 R2c, SH substituted with 0-1 R2c, Cl, F, NH2 substituted with 0-2 R2c, -CN, NO2, methanesulfonyl, C1-4 alkyl substituted with 0-2 R2c, C2-4 alkenyl substituted with 0-2 R2c, aryl substituted with 0-2 R2c, heteroaryl substituted with 0-2 R2c, C3-6 cycloalkyl substituted with 0-2 R2c and a heterocyl substituted with 0-2 R2c; R2c, at each occurrence, is selected from OH, SH, Cl, F, NH2, -CN, NO2, C1-4 alkyl, C2-4 alkenyl, aryl substituted with 0-2 R2d, and heteroaryl substituted with 0-2 R2d ; R2d, at each occurrence, is selected from OH, SH, Cl, F, NH2, -CN, NO2, C1-4 alkyl and C2-4 alkenyl; and R3 is selected from Cl, F, CH3 and CH2CH3. |
priorityDate | 2005-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 1065.