| abstract |
Modified lecithin-cholesterol acyltransferase (LCAT) protein, in which the modified LCAT protein comprises a modification in the mature LCAT amino acid sequence set forth in SEQ ID NO: 1; or SEQ ID NO: 2 as set forth in Figure 2; and the modification consists of a substitution in the C31 amino acid residue selected from the group consisting of C31I, C31M, C31F, C31V, C31W, C31Y, C31R and C31H. |