| abstract |
Compound having formula I: ** Formula ** or a pharmaceutically acceptable salt, solvate or stereoisomer thereof; or a tautomer or a pharmaceutically acceptable salt, solvate or stereoisomer thereof; or a mixture thereof, where X is 0; W, Y and Z are all C-H; R1 is selected from H, (C1-C6) alkyl, (C2-C6) alkenyl or (C2-C6) alkynyl; Rla is H; R2 is selected from F or alkoxy (C3-C6); R3 is alkoxy (Ci-C2); R4, R5 and R6 are independently selected from H and (C1-C4) alkyl groups and at least two of R4, R5 and R6 are (C1-C4) alkyl groups, and two of R4, R5 and R6 can be linked together to form a ring of 3 to 7 members; R7 and R8 are H; R9 and R1 ° are independently selected from H and alkyl (Ci-C4); each R11 is independently selected from F, Cl, (C1-C4) alkyl or (C1-C4) alkoxy and m is 0; Each R12 is independently selected from F, Cl, (C1-C4) alkyl or (C1-C4) alkoxy and n is 0. |