| abstract |
Compound of formula I: ** Formula ** a pharmaceutically acceptable salt thereof, or a solvate thereof, in which: n is 1 to 6; R1 is C1-6 alkyl; R2 is H; R3 and R4 are independently selected from H, C1-6 alkyl and hydroxymethyl; R5 is chosen from OH and C1-6 alkoxy; R6 is selected from H, OH, methoxy, ethoxy, propoxy, butoxy and cyclohexyloxy; each of R7, R8, R9 and R10 is independently selected from H, C1-6 alkyl, trifluoromethyl, C2-6 alkenyl, C2-6 alkynyl, methoxy, ethoxy, propoxy, butoxy, cyclohexyloxy, C (O) OH, CN , NO2, halogen, phenyl, fenilosustituido, naphthyl, benzothienyl, benzofuranyl, indolyl, isoxazolyl, substituted isoxazolyl, pyrazolyl, pyridazinyl, pyridazinyl substituted, pyridinyl, substituted pyridinyl, pyrimidinyl, substituted pyrimidinyl, quinolinyl, thiazole, substituted thiazole, thienyl, substituted thienyl , morpholinyl and piperidinyl, in which: the substituents in the substituted R7, R8, R9 and R10 groups are -X, -R33, -OR33, -CX3, -CF3, -CN, -C (O) R33 oC (O ) OR33, in which: X is halogen; and R33 is H, C1-6 alkyl, -NR35R36, phenyl, cyclohexyl, piperidinyl or pyrrolidinyl, wherein R35 and R36 are independently H or C1-6 alkyl. |