http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2445339-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e6af933919fad4bb75411810e6c3c25 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2005-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a35ab0c4c5504d480808856405cf7055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c35f7228511e4b26ce039531b93de2d4 |
| publicationDate | 2014-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2445339-T3 |
| titleOfInvention | Wnt proteins and cancer detection and treatment |
| abstract | A method for identifying an anti-liver cancer agent, the method comprising: selecting a test compound that binds to a polypeptide comprising an amino acid sequence of a Wnt3 or Wnt11 protein or an FZD binding fragment thereof; and determine if the test compound is capable of: (a) reducing Wnt / FZD 7 signaling in a liver cell; (b) reduce the motility of liver cancer cells; (c) reduce the accumulation of β-catenin in a liver cancer cell; or (d) treat liver cancer in vitro or in a non-human animal in vivo; wherein a test compound that is capable of at least one of (a) to (d) is an anti-liver cancer agent. |
| priorityDate | 2004-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 675.