http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2444011-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-56 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 |
filingDate | 2007-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2014-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76eaa8b82f08e5cc7292a4ca8014443d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d330363819b74a6709e886200ee292f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7345828696a9063794b35533252e12d4 |
publicationDate | 2014-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2444011-T3 |
titleOfInvention | Procedure and devices for the electrochemical determination of factor Xa inhibitors in blood samples |
abstract | Procedure for the determination of factor Xa inhibitors in blood samples, characterized in that a) a sample of the blood to be analyzed is contacted with a detection reagent, which contains, at least, a thrombin substrate, which consists of a peptide residue, which can be cleaved by lathrombin and is amically linked via the carboxyl terminus to an electrogenic substance and to a reagent containing a known amount of factor X and an activating reagent, causing the transformation of factor X into factor Xa, from such that the addition of the reagent containing a known amount of factor X to the sample takes place in a common step with the addition of the activating reagent to the sample, b) the amount or the activity of the electrogenic substance that is dissociated from the thrombin substrate by factor Xa-induced activation of thrombin and / or its behavior over time are determined as a measurement signal by procedures Electrochemical effects, and c) with the help of this measurement signal, the amount of factor Xa inhibitor in the blood sample to be analyzed or a measurement quantity correlated with it, in particular a coagulation time that is correlated with it, is determined. |
priorityDate | 2006-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 77.