http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2443845-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2010-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65db56cdc03fe4fa129dfbfe2d0ce57d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a94b0865bb9dfdca29aa7c52de6a0a7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3e1a0106b8602fa0b53dabf6136a732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3a51da8a65cac17df3f68f75600a339 |
| publicationDate | 2014-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2443845-T3 |
| titleOfInvention | Sulfonamides as protein inhibitors of the BCL-2 family for cancer treatment |
| abstract | A compound of formula I: wherein A is a divalent bicyclic radical comprising a saturated cyclic structure and an unsaturated cyclic structure, wherein said unsaturated cyclic structure is attached to NH, and said saturated cyclic structure is attached to R1, where A is not substituted or substituted with one or more substituents each independently selected from halogen, OH, (C1-C6) alkyl, (C1-C6) alkyl substituted with halo, CN, or NR10R11; R1 is 3- to 8-membered cycloheteroalkyl, (C3-C8) cycloalkyl, or a (C6-C14) aryl group which is unsubstituted or substituted with (C1-C6) alkyl, halogen, OR57, NR58R5, or deuterium; L1 is (C1- C3) alkylene, (C1- C4) alkenylene, -C (O) -, - C (O) O-, C (O) N-, - (C1- C3) alkylene C (O) - , - (C1-C3) alkylene-C (O) O-, or a bond, wherein L1 is unsubstituted or substituted by one or more substituents each independently selected from (C1-C4) alkyl, (C1-C4) alkyl substituted by halo, or (C3-C8) cycloalkyl; L2 is (C1-C3) alkylene, NR9, -O-, or -S-; R2 15 is (C6-C14) aryl, 5- to 14-membered heteroaryl, 3- to 8-membered cycloheteroalkyl, or (C3-C14) cycloalkyl, each of which is unsubstituted or substituted with one or more halogen, OH, (C1-C6) alkyl, (C1-C6) alkyl substituted with halo, or CN. |
| priorityDate | 2009-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 350.