http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2439969-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08 |
| filingDate | 2009-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ac7eacba374807feab484feb085af25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fc1b58f4f9603395c75ae2c2c2b0c2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e6de93399b16fca8512d7b71b40edec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5da5dea38a5b59e4f438b848a75314c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5df9d7e996793a85d4a746fdaa693d97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1f8a369915641529fb573156f80434c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_027b02953f27c8fe8bf305ffa3b10a8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aee0e0ef6e0905e6b0ad53f19d41ac52 |
| publicationDate | 2014-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2439969-T3 |
| titleOfInvention | New heterocyclic compounds for the treatment of cardiovascular diseases |
| abstract | Compounds of the formula (I) in which A is aryl, heteroaryl, arylmethyl or heteroarylmethyl, the aryl of said aryl and arylmethyl and the heteroaryl of said heteroaryl and heteroarylmethyl are optionally substituted one to three times by substituents chosen independently from the group formed by halogen, aryl, heteroaryl, C1-6alkyl, haloC1-6alkyl, C1-6alkoxy and C1-6haloalkoxy, or said aryl and heteroaryl are optionally substituted by C1-6alkylenedioxy; X is -N (R1) (R2); R1 and R2 are independently hydrogen, C1-6 alkyl, C3-6 alkenyl, C3-6 alkynyl, C2-6 hydroxyalkyl, (C1-6 alkoxy) -C2-6 alkyl, C3-7 cycloalkyl, (C3-7 cycloalkyl ) -C1-6alkyl, C7-10 bicycloalkyl, phenyl-C1-3alkyl, heteroaryl-C1-3alkyl, heterocyclyl or heterocyclyl-C1-6alkyl, wherein the cycloalkyl of said C3-7cycloalkyl and (C3 cycloalkyl -7) -C1-6alkyl, the phenyl of said phenyl-C1-3alkyl, the heteroaryl of said heteroaryl-C1-3alkyl and the heterocyclyl of said heterocyclyl and heterocyclyl-C1-6alkyl are optionally substituted one to three times by substituents chosen independently from the group consisting of Rd; or R1 and R2 together with the nitrogen atom to which they are attached form a heterocyclyl optionally substituted one to three times by substituents independently chosen from the group consisting of Rd, and one of the carbon atoms of said heterocyclyl ring formed by R1 and R2 has been optionally replaced by a carbonyl group; and / or one of the carbon atoms of the heterocyclyl ring formed by R1 and R2 may be a carbon atom of another ring that is C3-7 cycloalkyl or heterocyclyl, one or two carbon atoms of said other ring has been optionally replaced by a carbonyl group and said other ring is optionally substituted by C1-6 alkyl; R3 and R4 are independently hydrogen, hydroxy, C1-6alkyl, C1-6alkoxy, C3-7cycloalkyl, (C3-7cycloalkyl) -C1-6alkyl, (C1-6alkoxy) -carbonyl, carboxyl, carbamoyl, carbamoyl mono- or substituted by C1-6 alkyl, (C1-6 alkoxy) -carbonyloxy, aminocarbonyloxy mono- or substituted by C1-6 alkyl, (C1-20 alkyl) -carbonyloxy-C1-6 alkyl, (C1-20 alkoxy) -carbonyloxy-C1-6alkyl, arylcarbonyloxy-C1-6alkyl, aminocarbonyloxy-C1-6alkyl mono- or substituted by C1-6alkyl, aminocarbonyloxy-C1-6alkyl substituted by aryl, hydroxy-C1-6alkyl, C1-alkoxy -6-C1-6-alkyl, halogen or haloC1-6-alkyl, said aryl is optionally substituted one to three times by substituents independently chosen from the group consisting of halogen, C1-6-alkyl, C1-6-haloalkyl, C1-6-alkoxy and C1-6 haloalkoxy; or R3 and R4, together with the carbon atom to which they are attached form C3-7 cycloalkyl or heterocyclyl optionally substituted one to three times by substituents independently chosen from the group consisting of C1-4alkyl, C1-4alkylalkyl and halogen; Y1 is C (O) or S (O) 2; Y2 is O or S; Y3 is NH or O; p is the number 0 or 1. |
| priorityDate | 2008-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 835.