http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2439802-T3

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filingDate 2010-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f6ca3daf0d46fb23a444dfb51afb77a
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publicationDate 2014-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2439802-T3
titleOfInvention Tri- or tetra-specific antibodies
abstract Trispecific or tetra-specific antibody, comprising: a) the light chain and heavy chain of a full-length antibody that specifically binds to a first antigen, and b) the modified light chain and the modified heavy chain of a full-length antibody that specifically binds to a second antigen, in which the variable domains VL and VH are mutually substituted, and / or in which the constant domains CL and CH1 are mutually substituted, and c) wherein one to four antigen-binding peptides that specifically bind to one or two additional antigens are fused through a peptide linker with the C-terminal or N-terminal end of the light chains or heavy chains of a) and / or b).
priorityDate 2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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