http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2438727-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5ffa3f9d6b87e15e0a1551fb129b531 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-785 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-785 |
| filingDate | 2007-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2014-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dbb9fedee24085034ced4f661b4a458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eefe737a36f72df8699d75573d64efe3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8334008fc1e58309691df4dc2b9385a4 |
| publicationDate | 2014-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2438727-T3 |
| titleOfInvention | Reconstituted surfactants with improved properties |
| abstract | A reconstituted surfactant comprising a mixture of phospholipids and a combination of a polypeptide analog of native surfactant protein SP-C with a polypeptide analog of native surfactant protein SP-B wherein said polypeptide analog of native surfactant protein SP-C is a polypeptide of at least 20 amino acid residues and not more than 40 amino acid residues with the sequence represented by the general formula (I) FeGeIfPfSgSPVHLKRXaBXb (BXc) nGALLpGpLp (I) where X is an amino acid residue independently selected from the group consisting of I, L, and nL; B is an amino acid residue independently selected from the group consisting of K, W, F, Y, and Orn; S is optionally substituted with acyl groups containing 12-22 carbon atoms, preferably 16 carbon atoms, attached to the side chain through an ester bond; it is an amino acid selected from the group consisting of M or is oxidized at the sulfur atom, I, L, and nL; A is an integer that has a value from 1 to 8; B is an integer having a value from 1 to 19; C is an integer having an independently selected value from 3 to 8; e, f, g and p are integers that have a value of 0 or 1; N is an integer that has a value from 0 to 3; with the proviso that XaBXb (BXc) n is a sequence that has a maximum of 22 amino acids; and wherein said native surfactant protein polypeptide analog SP-B is a polypeptide of the general formula (II): CfΔLCRALIKRIQAIPKGGRLPQLVCRLVLΦCSf (II) wherein Δ is an amino acid residue selected from the group consisting of W and L; it is an amino acid residue independently selected from the group consisting of M, I, L, and nL; Φ is an amino acid residue selected from the group consisting of R and T; and f is an integer that has a value of 0 or 1. |
| priorityDate | 2006-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.