| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c6bf6e836559d0a2c9a2a3429dafdb7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6869 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2009-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41d5bc9eb0517fc0a1703700f9140bf2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8eb1fd7fe570be56507065ac70e3612
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_569be3037f44af5d5ab5c3c36ee322f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5784c040bf4eb620386db38190f3752 |
| publicationDate |
2014-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2438495-T3 |
| titleOfInvention |
Compounds to kill cancer cells expressing PSMA, resistant to taxane |
| abstract |
An in vitro method for exterminating cancer cells expressing PSMA, resistant to taxane, which comprises: contacting cancer cells expressing PSMA, resistant to taxane, with an antibody-drug conjugate in an amount effective to kill cancer cells expressing PSMA , resistant to taxane, in which the antibody-drug conjugate comprises a monoclonal antibody or its antigen-binding fragment that specifically binds to the prostate-specific membrane antigen (PSMA) conjugated to monomethylauristatin norephedrine or monomethylauristatin phenylalanine, and in which PSMA sequence is the sequence set forth in SEQ ID NO: 1. |
| priorityDate |
2008-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |