| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd5ab29f0d041de89e4d36e513f62edf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-01 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-485 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33 |
| filingDate |
2009-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56eccea9fcd5300a1743cf8e16203558
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fcd9065cd225c8f4ccc8c22fa28c578
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3252f33ec71c4ea2eca21a7d01e3a00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abb48773ff297632a86a599dd55578af
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_139ab5730da00633cc55ca031f2d50c7 |
| publicationDate |
2014-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2436816-T3 |
| titleOfInvention |
Non-cytotoxic fusion proteins comprising EGF muteins |
| abstract |
A polypeptide, comprising: a. a non-cytotoxic protease that is capable of cleaving a SNARE protein; b. a translocation peptide that is capable of translocating said non-cytotoxic protease from within an endosome of a mammalian cell, through the endosomal membrane thereof and into the cytosol of the mammalian cell; and c. an epidermal growth factor (EGF) mutein, wherein said EGF mutein comprises an amino acid sequence having at least 95% identity frequency with respect to the amino acid sequence of SEQ ID NO: 11 and wherein said mutein of the EGF retains the binding affinity of SEQ ID NO: 11 to bind to an EGF receptor. |
| priorityDate |
2008-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |