| abstract |
A compound of formula (I) below, or a pharmaceutically acceptable salt thereof: wherein R is H, C1-C4 alkyl or C1-C4 alkyl substituted with one or more groups independently selected from halo, hydroxyl, amino and azido; R1 is H, C1-C4 alkyl, C2-C4 alkenyl or C2-C4 alkynyl, wherein the C1-C4 alkyl, C2-C4 alkenyl or C2-C4 alkynyl are substituted or unsubstituted with one or more groups independently selected from halo , hydroxyl, amino and azido; and Ar is thiazolyl, imidazolyl, pyridyl, benzothiazolyl, oxadiazolyl, or benzotriazolyl, and is unsubstituted or monosubstituted or substituted by hydroxyl, halo, cyano, oxo, -N-C1-4alkyl,> = N-C1-alkoxy 4, amino, alkylamino, dialkylamino, acylaminoalkyl, alkoxy, thioalkoxy, C1-C4 alkyl, cycloalkyl or haloalkyl; with the proviso that when R is methyl or trifluoromethyl and Ar is then R1 is not H. |