http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2436267-T3
Outgoing Links
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59924c7203b1a1fa066ebf4f7696ad70 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00 |
filingDate | 2009-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7863c3c020bd769c1ec472e0f2862adf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b15ea1a6815ba7ec6ee0841dbd0af14c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b90d20f276c2aab8768a760cc16d6b |
publicationDate | 2013-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2436267-T3 |
titleOfInvention | Synthetic analogs phosphatidyl-myo-inositol mannosides with inflammatory response inhibitory activity |
abstract | Compound of the general formula (I): in which: - R1 and R2 represent, independently of one another, a hydrogen atom, a C1-C20 alkyl radical, a C1-C20 acyl radical, being understood as long as one of the R1 or R2 substituents is a hydrogen atom, the other substituent is different from that of hydrogen; - Z1 and Z2 represent, independently of each other, a hydrogen atom, at least one sugar selected from the group consisting of mannose, glucose, galactose being understood as long as one of the substituents Z1 or Z2 is a hydrogen atom, the other substituent be different from dehydrogen; - Q represents - OP (O) 2O -, - OCO2 -, NHCO2 -, NHCONH -; - Y represents a hydrogen atom, a hydroxyl radical, a C1-C6 alkoxy radical - (CH2) n - OH where n is an integer equal to 1, 2 or 3, being understood as long as Y is a hydroxyl radical; and Z1 and Z2 do not represent the two groups of a hydrogen atom; -A represents - CH2 -; - X represents a hydrogen atom; - or A and X form a link to lead to a 6-link cycle in which - A represents a - CH-, - X represents a - CH2 -, - CH (OH) -, an oxygen atom, a -NR3 - in which R3 is a hydrogen atom, a C1-C6 alkyl radical or a C1-C20 acyl radical, being understood as long as - A and X form a bond to lead to a 6-link cycle, - X> = - CH (OH) -, - Y> = - OH, and - Z1 and Z2 represent, independently of each other, at least one sugar selected from the group consisting of mannose, glucose and galactose the 6-member cycle has a myoinositol configuration with Z1 or Z2 in position 1 and represent, at least one sugar, knowing that "alkyl" refers to a carbonadolineal, branched or cyclic, saturated or unsaturated, optionally substituted radical, comprising 1 to 20 carbon atoms, knowing that "acyl" refers to a radical - COR- in which R- is an alkyl radical such and as defined above, knowing that "alkoxy" s e refers to a radical -OR- in which R- is an alkyl radical such and as defined above; or one of its pharmaceutically acceptable salts; knowing that "pharmaceutically acceptable salts" refers to salts prepared with acids or non-toxic bases. |
priorityDate | 2008-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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