http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2434116-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3de816347946552a9aaaf2eaea3e6d6 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-35 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
filingDate | 2008-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5037a9f67504399d51525325a3b1570 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e91add19593fe2b814499ba193af4e3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4350d0a6735399bf1432673c91dc9bb |
publicationDate | 2013-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2434116-T3 |
titleOfInvention | A new and effective pharmacological target for the treatment of tuberculosis |
abstract | Method for in vitro screening of candidate drugs for the treatment of tuberculosis by interference with the biosynthesis of arabinogalactan, wherein said method comprises a step of contacting a Mycobacterium tuberculosis cell culture that excessively expresses a protein that leads to the transformation of decaprenyl-P-ribose into decaprenyl-P-arabinose and which is encoded by the rv3790 gene or homologs thereof or any artificial open reading frame whose gene product is identical or homologous to the Rv3790 protein with a candidate drug and the subsequent evaluation of the percentage of inhibition caused by the candidate drug versus a control in an assay test. |
priorityDate | 2008-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 219.