| abstract |
Compound of formula ** Formula ** including any stereochemically isomeric form thereof, in which: A represents phenyl, thienyl, furanyl or a 6-membered aromatic heterocycle containing 1 or 2 nitrogen atoms; wherein said phenyl, thienyl, furanyl or 6-membered aromatic heterocycle may optionally be condensed with phenyl or a 6-membered aromatic heterocycle containing 1 or 2 nitrogen atoms; Z represents CH2 or O; R 1 represents halo, hydroxy, C 1-4 alkyl, C 1-4 alkyloxy, C 1-4 polyhaloalkyl, cyano, nitro, amino, mono or di (C 1-4 alkyl) amino; or in the case that A represents phenyl then two adjacent R1 substituents can be taken together to form a radical of -O-CH2-O- (a-1); or -O-CH2-CH2-O- (a-2); R2 represents hydrogen or C1-4 alkyl; R3 and R4 each independently represent hydrogen, C1-6 alkyl, C1-4 alkyloxy-C1-6 alkyl or phenylC 1-4 alkyl; or R3 and R4 are taken together with the nitrogen to which they are attached to form a radical of formula (b-1) or (b-2) ** Formula ** |