http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2432315-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a23a7e20fd8968919daca6d47ac689c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 |
| filingDate | 2010-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea2e39ea040cd24dec2108c63c7305ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_032150bf1b2a29ee694c84c9f7b84f96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b0e4c9f3cfe7d8e9db398fd71f0997f |
| publicationDate | 2013-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2432315-T3 |
| titleOfInvention | Hexahydrooxazinopterin compounds for use as mTOR inhibitors |
| abstract | Compound of formula ** Formula ** G1 is selected from the group consisting of N and CR7; G2 is selected from the group consisting of C> = O and CH2; Ar is selected from the group consisting of C4-14 aryl and C1-10 heteroaryl; m is 0, 1, 2, 3 or 4; R1 is independently selected, taken each time, from the group consisting of halo, cyano, optionally substituted C1-6 alkyl, C1-8 sulfonyl, optionally substituted C2-4 alkenyl, optionally substituted C2-4 alkynyl, optionally substituted C1-4 alkoxy, alkylamino C0-8, optionally substituted C4-14 aryl, optionally substituted C4-14 aryloxy, optionally substituted C1-10 heteroaryloxy, C1-5 oxycarbonyl, C1-5 carbonyloxy, optionally substituted C3-8 cycloalkyl, optionally substituted C3-6 heterocycloalkyl, heteroaryl Optionally substituted C1-10, hydroxyl, nitro, -C (O) NR8R9, -NHC (O) NR8R9, -NHC (O) OR10, -NH (SO2) NHR8, -NHC (O) NHNR8R9, -NHC (S) NR8R9, -NHC (> = NR11) NR8R9, -NHC (SR12) NR8R9 and-NHC (> = NR11) OR13; R2 is selected from the group consisting of hydrogen, halo, cyano, optionally substituted C1-6 alkyl, C1-8 sulfonyl, optionally substituted C2-4 alkenyl, optionally substituted C2-4 alkynyl, optionally substituted C1-4 alkoxy, C0-8 alkylamino , optionally substituted C4-14 aryl, optionally substituted C4-14 aryloxy, C1-5 oxycarbonyl, C1-5 carbonyloxy, optionally substituted C3-6 heterocycloalkyl, optionally substituted C1-10 heteroaryl, hydroxy and nitro; R3 is selected from the group consisting of hydrogen, optionally substituted C1-6 alkyl, optionally substituted C3-8 cycloalkyl and optionally substituted C3-6 heterocycloalkyl. |
| priorityDate | 2009-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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