http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2427852-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3434865446cb768b1dc8dcb327ffb857 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate | 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a00abeb0ed5db70615f759c900bcc1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0745def1ec9af4f26f447768553d807 |
| publicationDate | 2013-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2427852-A1 |
| titleOfInvention | Calcium sensors and methods for the detection of intracellular free calcium |
| abstract | Calcium sensors and methods for the detection of intracellular free calcium. # The invention provides a calcium sensor based on a fusion protein comprising (i) a first polypeptide domain capable of binding Ca {sup, 2 +}, (ii ) a second polypeptide domain of the sequence SEQ ID NO: 1 (GFPuv) or a variant thereof that maintains two maximums in its excitation spectrum and at least one maximum in its emission spectrum, and (iii) a flexible peptide that unites the first domain and the second domain covalently. It also provides a transgenic non-human animal that comprises the fusion protein. Also, the invention provides methods for detecting the intracellular Ca {sup, 2 +} calcium concentration. |
| priorityDate | 2012-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 654.