abstract |
A method for identifying in vitro a compound that induces anabolic stimulation of chondrocytes, which comprises - contacting a compound with a polypeptide comprising an amino acid sequence selected from the group consisting of sec. with no. of ident .: 126 and 127; and - measuring a property of the compound-polypeptide related to anabolic stimulation of chondrocytes in which, preferably, said polypeptide is in a cell-free preparation in vitro or dichopolypeptide is present in a mammalian cell. |