http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2426011-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-54 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 |
| filingDate | 2006-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abdfe9f4bc574d2b9f3f4298600ef3d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36604fd0b1776be17ce826816302c7d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16c381c655fccfd16ccf663e9fe6d4c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ff91b47c43b054d01fd9343d9fb061a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be130956655882e224a3ae5e0441c68c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caeeda5914c5ce2b7db3dfdf2d39f60c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ce2d0c713f1909f9398e6ca90686804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6d5f77b3fb342202e8fc538fa0c85a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94c6ab36d257fa3c4de91d7c1a283610 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd66e2cca5cb51bcb2c893734e9db9de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b4f66d61cfb3eea00f21ae52ce24da6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb5675788b6b811130cbd3e327a36907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bdd45507cf4acde8a60ec9bfb93a0d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5ae991159634994e2322ca95faae1f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a91aede18f55dfbbcb0e616a1da81e92 |
| publicationDate | 2013-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2426011-T3 |
| titleOfInvention | 11-beta-hydroxysteroid dehydrogenase-1-diabetes inhibitor type 2-1 |
| abstract | A compound of formula (I): wherein: R1 is aryl, heteroaryl, aralkyl, heteroaralkyl, lower alkyl, lower alkoxy-benzyl, lower alkoxy-carbonylalkyl lower, haloalkyl lower, hydroxy-lower alkyl, (lower alkoxy-lower alkyl), ( CH2) s-aryl, (CH2) sheteroaryl or (CH2) s-cycloalkyl, wherein said aryl, heteroaryl, aralkyl, heteroaralkyl (CH2) s-aryl, (CH2) sheteroaryl (CH2) s-cycloalkyl is substituted or without substitute with one or more substituents selected from the group consisting of halogen, lower alkyl, lower alkoxy, cyano, lower alkoxycarbonyl, halo lower alkyl, phenyl- (oxo-lower alkyl) and hydroxy-lower alkyl; p is 0 or 1; s is 0, 1 or 2; and R2 is phenyl, which may be unsubstituted or substituted by one or more substituents selected from the group consisting of halogen, hydroxy, haloalkyl lower, lower alkoxy, trifluoromethoxy, aminocarbonyl, lower alkyl, nitro, cyano, sulfonamido, alkyl- lower sulfonyl, lower acyl and lower alkoxycarbonyl, lower haloalkyl, substituted or unsubstituted naphthyl, biphenyl, which may be unsubstituted or substituted with one or more substituents selected from the group consisting of acetyl, halogen, lower alkoxy and lower alkyl, a monocyclic heterocycle 5- or 6-membered with 1-3 atoms selected from N, O, and S, which may be unsubstituted or substituted by halogen, lower alkyl, substituted or unsubstituted phenyl, or substituted or unsubstituted haloalkyl, obenzothiophene, and wherein the term "alkyl" means a branched or unbranched, cyclic or acyclic, saturated hydrocarbyl radical (partially saturated if is cyclic) or unsaturated which may be substituted or unsubstituted; the term "aryl" is used to mean a mono- or polycyclic aromatic ring system, where the rings may be carbocyclic or may contain one or more atoms chosen from O, S, and N; the term "lower alkyl" means a branched or unbranched, cyclic or acyclic, saturated (partially saturated if cyclic) or unsaturated hydrocarbyl radical wherein said cyclic lower alkyl group is C3, C4 C5, C6 or C7, and wherein said lower alkyl group is C1 C2, C3 or C4; with the proviso that the following compounds are excluded: 1,7,8,8-Tetramethyl-2-phenyl-1,2,4,5,6,7-hexahydro-4,7-methane-indazol-3-one , 1,7,8,8-Tetramethyl-2-naphthalen-1,2,4,5,6,7-hexahydro-4,7-methane-indazol-3-one, 1,7,8,8-Tetramethyl -2-p-tolill-1,2,4,5,6,7-hexahydro-4,7-methane-indazol-3-one, 2- (4-Methoxy-phenyl) -1,7,8,8 -tetramethyl-1,2,4,5,6,7-hexahydro-4,7-methane-indazol-3-one and 1,7,8,8-Tetramethyl-2-o-tolyl-1,2,4 , 5,6,7-hexahydro-4,7-methane-indazol-3-one. |
| priorityDate | 2005-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 756.