| abstract |
A compound according to formula II for use in the treatment or prevention of malignant ascites caused by ovarian cancer: wherein R 1 is H, straight or branched chain alkyl, alkenyl, alkenyl alkyl, cycloalkyl, cycloalkylalkyl, cycloalkenyl alkyl, aryl, arylalkyl, -SR7, -SOR8, -SO2R9, -SCN, -B '(CH2) nBR10, -C (O) -R11, -OR12, -COOR13, -NO2, -NR13aCOOR13b, isothiocyanate or -CN, where R7 to R13b are each independently H, chain or branched alkyl, alkenyl, alkenyl alkyl, cycloalkyl, cycloalkylalkyl, cycloalkenyl alkyl, aryl or arylalkyl, B and B 'are independently O, S, S (O) or SO2 and n is 1 to 4; and R21 is H, straight or branched chain alkyl, alkenyl, alkenyl alkyl, cycloalkyl, cycloalkylalkyl, cycloalkenyl alkyl, aryl or arylalkyl. |