http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2425344-T3

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0059
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filingDate 2011-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3170e61892f7aa425e74fc601dc10863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68387099ebc886627e87cc6b6f63c273
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publicationDate 2013-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2425344-T3
titleOfInvention A process to introduce a double bond at position 15,16 of a steroid
abstract A process for the preparation of a compound of formula (I): ** Formula ** where R1 is a (C1-C4) alkyl and R2 is H or methyl, which comprises the reaction of a compound of formula (II) with a base: ** Formula ** where: R1 and R2 are as defined above; R3 is -COR4, R4 is a (C1-C6) alkyl, a phenyl optionally substituted with 1 to 3 (C1-C4) alkyl or a benzyl in which elphenyl is optionally substituted with 1 to 3 (C1-C4) alkyl; where the base is selected from a metal carbonate; a metal bicarbonate; a metal hydroxide; metal unhydride; a metal acetate; ammonia; and an amine of formula NR5R6R7 where each of R5, R6 and R7 independently represents H; a (C1-C6) alkyl optionally substituted with unhydroxy; or a cycloalkyl (C3-C6) (and at least one of R5, R6 and R7 is not H); or R5 is H and R6 and R7 form, together with the nitrogen atom to which they are attached, a saturated heterocycle of 5 to 7 members that may optionally contain other heteroatoms selected from O and N.
priorityDate 2010-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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