http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2425344-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a48132fcc2f50a7107021f911f887cb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-0059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 |
filingDate | 2011-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2013-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3170e61892f7aa425e74fc601dc10863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68387099ebc886627e87cc6b6f63c273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50db5be34fa4ba106190a15f382f22c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d52a661b977910edb4c2f9d4176cd77c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96461a0a80f9ef0f8d21f36e3b1ca6d2 |
publicationDate | 2013-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2425344-T3 |
titleOfInvention | A process to introduce a double bond at position 15,16 of a steroid |
abstract | A process for the preparation of a compound of formula (I): ** Formula ** where R1 is a (C1-C4) alkyl and R2 is H or methyl, which comprises the reaction of a compound of formula (II) with a base: ** Formula ** where: R1 and R2 are as defined above; R3 is -COR4, R4 is a (C1-C6) alkyl, a phenyl optionally substituted with 1 to 3 (C1-C4) alkyl or a benzyl in which elphenyl is optionally substituted with 1 to 3 (C1-C4) alkyl; where the base is selected from a metal carbonate; a metal bicarbonate; a metal hydroxide; metal unhydride; a metal acetate; ammonia; and an amine of formula NR5R6R7 where each of R5, R6 and R7 independently represents H; a (C1-C6) alkyl optionally substituted with unhydroxy; or a cycloalkyl (C3-C6) (and at least one of R5, R6 and R7 is not H); or R5 is H and R6 and R7 form, together with the nitrogen atom to which they are attached, a saturated heterocycle of 5 to 7 members that may optionally contain other heteroatoms selected from O and N. |
priorityDate | 2010-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.