| abstract |
Method for the production of hydroxiectoin The present invention relates to an isolated polynucleotide comprising the genes for the production of ectoin and hydroxiectoin, preferably with at least two copies of the gene coding for the enzyme ectoine hydroxylase, and whose expression is directed by at least one active promoter in conditions of low salinity and temperature. In addition, the present invention relates to the vector and the cell comprising said polynucleotide, and to a method of producing ectoin and hydroxiectoin based on said cell. Preferably, said cell is of the Chromohalobacter salexigens species and is unable to express the native ectA, ectB, ectC and ectD genes. |