abstract |
The present invention relates to a multicomponent chimera, HISA70, comprising 6 genes from Leishmania infantum: H2A, H2B, H3, H4, A2 and HSP70. Likewise, it is related to an immunogenic composition comprising said multicomponent chimera and the use of said composition in the preparation of a vaccine against Leishmania spp., To confer protection against leishmaniasis, including cutaneous leishmaniasis and visceral leishmaniosis, to mammals |