http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2415430-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-08 |
| filingDate | 2009-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f696b327b44f0d5f1c61cd7a96d83b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87d1754f1dd9b35913badd501a436e02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb6e8fe9352689508daf959188806fcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_114a465944b02b80187e2e38dfd6c14c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ca8b2a045946397e5f7dac74c744126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1df6876f05cc95231454620ba4e0a9c9 |
| publicationDate | 2013-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2415430-T3 |
| titleOfInvention | 3-Aminocyclopentanecarboxamides as chemokine receptor modulators |
| abstract | A compound of Formula I (a) or I (b): or a pharmaceutically acceptable salt thereof, in which: A is O or CF2; W is CR13R14, C (O), CHOR15, CHF, CF2, O or S R1 is H or (C1-C6) alkyl optionally substituted with 1-3 substituents selected from halo, OH, CO2H, CO2 (alkyl - (C1- C6)) or (C1-C3) alkoxy; R2 and R3 are each, independently, H, (C1-C6) alkyl, halo (C1-C4) alkyl, halo, (C3-C6) cycloalkyl, CN, OH, OCOR12; wherein said (C1-C6) alkyl is optionally substituted with one or more substituents selected from F, (C1-C3) alkoxy, OH, CN or CO2R12; R8 and R9 are each, independently, H, (C1-C6) alkyl, halo (C1-C6) alkyl, (C3-C6) cycloalkyl, CN, OH, OCOR12; wherein said (C1-C6) alkyl is optionally substituted with one or more substituents selected from F, (C1-C3) alkoxy, OH, CN or CO2R12; R2 and R8, taken together can form a 5-8 member ring; R4 and R7, taken together can form a 5-8 member ring; R4 and R5 are each independently H, CN, (C1-C6) alkyl, halo, (C1-C3) alkoxy, (C1-C3) haloalkoxy, (C3-C6) cycloalkyl, OH, CO2R12, OCOR12, in wherein said (C1-C6) alkyl is optionally substituted with one or more substituents selected from F, (C1-C3) alkoxy, OH or CO2R12; R6 and R7 are each, independently, H, CN, (C1-C6) alkyl, halo; (C1-C3) alkoxy, (C1-C3) haloalkoxy, (C3-C6) cycloalkyl, OH, CO2R12, OCCR12, wherein said (C1-C6) alkyl is optionally substituted with one or more substituents selected from F, (C1 -C3), OH or CO2R12; or R2 and R3 together with the carbon atom to which they are attached form a 3-7 membered spirocyclyl group; or R4 and R5 together with the carbon atom to which they are attached form a 3-7 membered spirocyclyl group; or R3 and R4 together with the C atoms to which they are attached form a 3-7 condensed cycloalkyl group or a 3-7 membered heterocycloalkyl group; R10 is (C1-C6) alkyl, halo (C1-C6) alkyl, hydroxyalkyl (C1-C6), alkoxy (C1-C6), cycloalkyl (C3-C6), hydroxycycloalkyl (C3-C6), alkoxy cycloalkyl, OH, heterocyclyl (C1-C5), amino, aryl or CN, R11 is aryl or heteroaryl, said R11 optionally, independently substituted with one or more (C1-C6) alkyl, halo, halo (C1C6) alkyl, (C1-C3) alkoxy, OH , amino, C (O) NH2, NH2SO2, SF5 or CN; R12 is H, alkyl, (C1-C4) or cycloalkyl (C3-C6); R13 is H, halo, (C1-C4) alkyl, (C1-C4) alkoxy or OH; R14 is H, halo, (C1-C4) alkyl, (C1-C4) alkoxy or OH; and R15 is H, (C1-C6) alkyl or (C3-C6) cycloalkyl wherein aryl is an aromatic carbocyclic group such as phenyl, biphenyl, indenyl, naphthyl; or an aromatic carbocycle condensed with a heterocycle such as benzothienyl, benzofuranyl, indolyl, quinolinyl, benzothiazole, benzooxazole, benzoimidazole, isoquinolinyl, isoindolyl, benzotriazole, indazole and acridinyl. |
| priorityDate | 2008-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 795.