abstract |
A recombinant high mobility group polypeptide, or a fragment thereof, comprising: a mitochondrial transcription factor A (TFAM) polypeptide comprising at least one HMG box operably linked to a protein transduction domain that is operably linked to a signal Target selector for a non-nuclear organelle, in which the recombinant polypeptide from the high mobility group can be associated with a polynucleotide to package the polynucleotide for delivery to the non-nuclear organelle. |