http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-240563-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ab824980d74d4ef98d1f395f1b25fd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_64d4a56b8c3032bcc981a4ae15e686a3 |
| filingDate | 1958-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1958-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-240563-A1 |
| titleOfInvention | PROCEDURE FOR PREPARING 21-ACILOXI-17-ALPHA-OXY-3-CETOESTEROIDES |
| abstract | Process for introducing a 21-acyl-xi group into the molecule of a 17alpha-oxy-3-ketosteroid of the pregnane or alopregnan series, which corresponds to formula I of the table, where R represents hydrogen or also an oxhydrolytic group with alpha or beta orientation and also a ketonic group, characterized in that said 3-keto-21-deoxy-steroid is reacted with a hydrocyanic acid donor capable of selectively blocking the 3-position ketone group the mono-cyanohydrin form; then the 3-mono-cyanohydrin of 21-deoxy-steroid is subjected to a treatment with bromine, in solution with a suitable organic solvent, to obtain the corresponding 3-mono-cyanohydrin of the 21-bromo-derivative, of which by substitution of the bromine atom by an acyloxy group and removal of the hydrocyanic acid from the molecule, a 21-acyloxy-17alpha-oxy-3-keto-steroid of the pregnane or alopregnan series corresponding to the formula V of the board. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1958-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.