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filingDate 2006-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2013-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35c418614bbea73979a44b270ca44bc5
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publicationDate 2013-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2402206-T3
titleOfInvention Formulation of 3- (2-dimethylaminomethyl-cyclohexyl) phenol of delayed effect
abstract Dosage form for controlled release Dosage form for controlled release of the active substance 3- (2-dimethylaminomethylcycloa of the active substance 3- (2-dimethylaminomethylcyclohexyl) phenol or of a pharmaceutically hexyl phenol salt or of a pharmaceutically compatible salt thereof , which - releases in vitro, measured ace compatible, which - releases in vitro, measured in accordance with the European Pharmacopoeia with an apparatus in accordance with the European Pharmacopoeia with a pH 6.8 pallet agitator stirring device, a paddle temperature entampon of pH 6.8, a temperature of 37 ° C and at 75 rpm, - after 0.5 hours of ra of 37 ° C and at 75 rpm, - after 0.5 hours from 9.0 to 31% by weight, - after 1 hour from 20 to 9.0 to 31% by weight, - after 1 hour from 20 to 48% by weight, - after 2 hours from 31 to 65% by 48% by weight, - after 2 hours from 31 to 31 65% by weight, - after 3 hours from 42 to 76% by weight, weight, - after 3 hours from 42 to 76% by weight, - after 4 hours from 50 to 83% by weight, - from - after 4 hours from 50 to 83% by weight, - after 6 hours from 60 to 94% by weight, - after after 6 hours from 60 to 94% by weight, - after 8 hours from 71 to 99% by weight, - after 12 to 8 hours from 71 to 99% by weight, - after 12 hours more than 79% by weight weight, of the active substance you will know more than 79% by weight, of the active substance originally contained in the dosage form, originally had in the dosage form, - includes a polymer matrix based on an ether - includes a polymer matrix based on an ether or cellulose ester, which in a concentration of the cellulose ester or ester, which in a concentration of 2.0% by weight in aqueous solution at 20 ° C has a 2.0% weight in aqueous solution at 20 ° C has a viscosity between 3,000 and 150,000 mPa · s, being in viscosity between 3,000 and 150,000 mPa · s, at least a part of the active ingredient capsul being encapsulated at least a part of the active ingredient in the polymeric matrix, the proportion in peen being the polymeric matrix, the proportion by weight of the polymeric matrix being from 5 to 85% by weight of the polymeric matrix from 5 to 85% by weight with respect to the total weight of the dosage form with respect to the total weight of the dosage form, and the cellulose ether or ester dn being selected, and the cellulose ether or ester being selected from the group consisting of methylcellulose, etie among the group consisting of methyl cellulose, ethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulol cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose and hydroxypropyl methyl cellulose, carboxymethyl cellulose and hydroxypropyl methyl cellulose. bear.
priorityDate 2005-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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