http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2401550-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2009-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eac9f18b127f51084a1b4b07dc9e6356 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6535263e1a4dcd82b9022a7515a27a59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1066f3f03a6cd7d646c78ad971d32735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_929b318e94c2e38925f8328e5f407510 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_643cfac8a2d2517522f2c14b2f9a8f86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22265d1fc44fd13f03680f63ec61cac1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3abf44002593d219fb8c537a373fd6ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ea441b31de70946f5c64f4a8bbd1e53 |
| publicationDate | 2013-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2401550-T3 |
| titleOfInvention | Protein kinase inhibitors and use thereof |
| abstract | A compound according to formula I wherein W is selected from Hal, Ar-alq, Het-alq, O, OH, SH, S (O) mZ, S (O) mAr, S (O) mHet, Z, OZ, OAr, OHet, OAlq or NRR '; Q is N or NH to satisfy the appropriate valence X is selected from N or [N + -O-]; ---------- indicates a single or double link; R1, R2, R3, R4, R5 and R6 are independently selected from hydrogen, Hal, Z, OZ, OAr, OHet, OH, NRR ', Ar, Aralq, Het, Het-alq, S (O) mZ, S ( O) mAr, S (O) mHet, C (O) mOR, NRC (O) mR ', NRSO2R', NRC (O) mNR ', (CH2) nOZ oC (O) NRR'; R and R 'are independently selected from hydrogen, Z, Ar, Ar-alq, Het, Het-alq, OZ, OAr, S (O) mZ, S (O) mAr or S (O) mHet; Z indicates branched or unbranched alkyl having 1-10 C atoms, in which 1-7 H atoms can be replaced by F, Cl and / or Br, and / or in which one or two non-adjacent CH2 groups are they can replace by groups O, N, NH, S, SO, SO2, and / or CH> = CH, or cyclic alkyl having 3-7 C atoms; Ar indicates phenyl, naphthyl, or biphenyl, each of which is unsubstituted or mono-, di-, or trisubstituted by Hal, Z, OR, N (R) 2, SR, NO2, CN, COOR, CON (R) 2 , NRCOZ, NRSO2Z, SO2N (R) 2, S (O) mZ, CO-Het, Het, O [C (R) 2] nN (R), O [C (R) 2] nHet, NHCOOZ, NHCON ( R) 2, NHCOO [C (R) 2] nN (R) 2, NHCOO [C (R) 2] pHet, NHCONH [C (R) 2] nN (R) 2, NHCONH [C (R) 2] pHet, OCONH [C (R) 2] nN (R) 2, OCONH [C (R) 2] nHet, CHO and / or COZ; Hal denotes Cl, Br, I, or F Het independently denotes a saturated, unsaturated, or aromatic mono-, bi-, or tricyclic heterocycle having 1 to 4 atoms of N, O, and / or S, which may be unsubstituted or mono- , di- or trisubstituted by Hal, Z, OR, (CH2) pN (R) 2, SR, NO2, CN, COOR, CON (R) 2, O [C (R) 2] nN (R), O [ C (R) 2] nHet1, NHCOOZ, NHCON (R) 2, NHCOO [C (R) 2] nN (R) 2, NHCOO [C (R) 2] nHet, NHCONH [C (R) 2] nN ( R) 2, NHCONH [C (R) 2] nHet, OCONH [C (R) 2] nN (R) 2, OCONH [C (R) 2] nHet, NRCOZ, NRSO2Z, SO2N (R) 2, S ( O) mZ, CO-Het, CHO, COZ,> = S,> = NH,> = NZ, oxy (-O-) and / or> = O (carbonyl oxygen). |
| priorityDate | 2008-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 3057.