| abstract |
An antibody, comprising the following domains: GYSITSGYSWH (amino acids 44 to 54 of Figure 1a) or SGYSWH (amino acids 49 to 54 of Figure 1a), HIHFSGRPTYNPSLSS (amino acids 69 to 84 of Figure 1a), KGKGSDDGLNY (amino acids 117 to 127 of Figure 1a), SASSSLSYIH (amino acids 46 to 55 of Figure 1c), DTSNLAS (amino acids 71 to 77 of Figure 1c), and FQGSEYPLT (amino acids 110 to 118 of Figure 1c), in which the union of the Antibody to a cell is capable of inducing cell death without the need for immune-sensing cells. |