http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2399241-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2786720cd363efcd84f5fd6492510e49 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2005-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d38a93d0f52d4c081864e942b81b5c54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3534169fbf99ea6875ec691d50a8ad7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0b2b3e15f01761d75facd53ec5fa6ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ec6cb71ee0ef4598d75d9bb40639c54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a214304e50f935db373aaa2b5556717 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2669071eaa2a1f30b55f2c854d6ce223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faf6b24f62153f218b7b8f4690ec6ab9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50bb99dfe6d04f4908dd51dea441104d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb265ce6ae7ab762df55568420b02afd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0e420944b709cd065ad8f2558beb828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae12b034eeb864f42b998750822af9cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99c0262c97dfbe3c12852f27d8b36f25 |
| publicationDate | 2013-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2399241-T3 |
| titleOfInvention | Triazole compounds that modulate the activity of HSP90 |
| abstract | A compound represented by the following structural formula: or a pharmaceutically acceptable tautomer, or a pharmaceutically acceptable salt, solvate or clathrate thereof, in which: ring A is an aryl or a heteroaryl, in which the aryl or heteroaryl are optionally further substituted with one or more substituents in addition to R3; R1 and R3 are, independently, -OH, -SH, -NR7H, -OR26, -SR26, -NHR26, -O (CH2) mOH, -O (CH2) mSH, -O (CH2) mNR7H, -S (CH2 ) mOH, -S (CH2) mSH, -S (CH2) mNR7H, -OC (O) NR10R11, -SC (O) NR10R11, -NR7C (O) NR10R11, -OC (O) R7, -SC (O) R7, -NR7C (O) R7, -OC (O) OR7, -SC (O) OR7, -NR7C (O) OR7, -OCH2C (O) R7, -NR7CH2C (O) R7, -OCH2C (O) OR7 , -NR7CH2C (O) OR7, -OCH2C (O) NR10R11, 10 NR7CH2C (O) NR10R11, -OS (O) pR7, -SS (O) pR7, -S (O) pOR7, -NR7S (O) pR7, -OS (O) pNR10R11, -SS (O) pNR10R11, -NR7S (O) pNR10R11, -OS (O) pOR7, -SS (O) pOR7, -NR7S (O) pOR7, -OC (S) R7, - SC (S) R7, -NR7C (S) R7, -OC (S) OR7, -SC (S) OR7, -NR7C (S) OR7, -OC (S) NR10R11, -SC (S) NR10R11, -NR7C (S) NR10R11, -OC (NR8) R7, -SC (NR8) R7, -NR7C (NR8) R7, -OC (NR8) OR7, -SC (NR8) OR7, -NR7C (NR8) OR7, -OC ( NR8) NR10R11, -SC (NR8) NR10R11, -NR7C (NR8) NR10R11, -OP (O) (OR7) 2 or -SP (O) (OR7) 2; R5 is an optionally substituted heteroaryl or an optionally substituted 8 to 14 membered aryl; R7 and R8, for each occurrence, are independently -H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl or an optionally substituted heteroralkyl; R10 and R11, for each occurrence, are independently -H, an optionally substituted alkyl, an optionally substituted alkenyl, an optionally substituted alkynyl, an optionally substituted cycloalkyl, an optionally substituted cycloalkenyl, an optionally substituted heterocyclyl, an optionally substituted aryl, a heteroaryl optionally substituted, an optionally substituted aralkyl or an optionally substituted heteroralkyl; or R10 and R11, taken together with the nitrogen to which they are attached, form an optionally substituted heterocyclyl or an optionally substituted heteroaryl; R26 is a C1-C6 alkyl; p, for each occurrence, is, independently, 0, 1 or 2; and m, for each occurrence, is independently 1, 2, 3 or 4; with the proviso that ring A is not a substituted [1,2,3] triazole; and with the proviso that the compound is not 3- (2,4-dihydroxy-phenyl) -4- (naphthalen-1-yl) -5-mercapto-triazole. |
| priorityDate | 2004-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 1933.