| abstract |
Compound of formula (I): or any pharmaceutically acceptable salt thereof, in which: each of X1, X2, X3 and X4 is independently N or C; in which no more than two of X1, X2, X3 and X4 are N; X5 is C; each of X6, X7, X9 and X10 is independently N or C; each of X8 and X11 is C; in which no more than X6, X7, X9 and X10 are N; Y is NH, NR5, CH (OH), C (> = O), -CRaRb or CF2; or alternatively Y and R3 forms a 5 to 6 member ring condensed with the ring containing both said Y and R3; Z is NH, NR6, S, SO, SO2 or O; m is 0, 1, 2, 3 or 4; n is 0, 1 or 2; p is 0, 1 or 2. |