http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2395606-A9
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7da5c8e8c3e8261efe7e698c7198681b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06 |
| filingDate | 2011-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d9af312d9d897865a498a6727840a77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b0686056e19f89d017647884bec6fe6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c148e44a6bb932a4e0f58d7872e4e29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e4f1418812c5454dd512e8d7206232a |
| publicationDate | 2014-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2395606-A9 |
| titleOfInvention | CHEMICAL PROCESS FOR SELECTIVE MODIFICATION OF PEPTIDES. |
| abstract | Chemical process for the selective modification of peptides # Procedure of selective modification of a peptide of general formula (30) to obtain a peptide of general formula (31) where [aa] {sub, n} represents the N-terminal end of the peptide with a variable number n of amino acids, [aa] {sub, m} represents the C-terminal end with a variable number m of amino acids, and the sum of m + n is an integer value between 1 and 50, and choose between -CH {sub, 2} -, -CH (alkyl) - and? C (= O) -, Z is chosen from hydrogen or an amine protecting group, and [A] {sub, i} is chosen from groups where A represents CH {sub, 2}, a substituted carbon or a heteroatom, and i represents an integer value between 1 and 10; characterized in that said process comprises the steps of [a] oxidative radical cleavage of the peptide of general formula (30) and [b] addition of a carbon nucleophile to the iminium intermediate formed to obtain a peptide of general formula (31). As well as the peptides of formula (31) obtained by this procedure and peptides derived from them. |
| priorityDate | 2011-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.