| abstract |
A compound, a tautomer of the compound, or a pharmaceutically acceptable salt of the compound or tautomer, wherein the compound is selected from the group consisting of: a compound having Formula II: wherein: R6 is selected from the group consisting of hydrogen and cyano; R8 is selected from the group consisting of hydrogen and arylalkyl; R25 is selected from the group consisting of hydrogen and alkyl; R37 is selected from the group consisting of hydrogen, alkyl, hydroxyalkyl, and cycloalkyl; R42 is selects from the group consisting of arylsulfanyl, heteroarylsulfanyl, and aryloxy; wherein R42 is optionally substituted with one or more substituents independently selected from R46; R46 is one or more substituents selected from the group consisting of hydrogen, hydroxy, amino, halogen, dialkylamino, and alkoxycarbonylamino; R70 is selected from the group that it consists of aryl, and heterocycle; wherein R70 is optionally substituted with R75; R75 is one or more substituents independently selected from the group consisting of hydrogen, halogen, alkoxy, cyano, alkyl, haloalkyl, and aryl. a compound having Formula III: |