| abstract |
A compound according to Formula I ** Formula ** wherein R1 and R2 are independently H or C1-C4 alkyl substituted or unsubstituted; R3 is H; -CF3; -C2F5; C1-C4 alkyl; C1-C4 alkenyl; C1-C4 alkynyl; -CH2-Z or R2 and R3 together with the nitrogen form a het ring; Z is H; -OH; F; Cl; -H3; -CF3; -CH2Cl; -CH2F or -CH2CH; R4 is straight or branched C1-C16 alkyl, or C3-C10 cycloalkyl, wherein the alkyl or cycloalkyl can be substituted or substituted, R5 is H; C1-C10 alkyl; C1-C10-aryl alkyl; -C (O) - (CH2) 0-6-phenyl; - (CH2) 0-6-C (O) -phenyl; aryl; indanyl; Naphthyl or R5 is an amino acid residue, wherein the alkyl or aryl substituents are substituted or unsubstituted; U is a bicyclic saturated or unsaturated ring system as shown in structure III: wherein any of the carbon atoms in the ring it can be substituted or not replaced with any of the substituents defined below for R6, R7, R8, and R7 '. |