http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2394364-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_baee372c55802742f9582e25c15ff11a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 |
| filingDate | 2006-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8f1c9ff368af18b43c14576190947a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8404ac25475157896f4efba201e1b30b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33e727da03da3b52b8cba3e4d65356ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f278d84c5a9f670b307540de54634b4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7268b63f41bd8533be7c40f2fe318b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b18c9f82f344ce58c1a728a01a1834d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eaccf9a29cd77cb1e1d983082e8056f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5559847434048a77f451260c10203b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddfa5d9c06abaadaf92101a07b1b517f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15c177742a40beb2926bfb0c920b38e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfcbf61b674cc586ab54b6c15ca4fe68 |
| publicationDate | 2013-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2394364-T3 |
| titleOfInvention | Bicyclic cinnamide derivative |
| abstract | A compound represented by formula (I): or a pharmaceutically acceptable salt thereof, in which it represents a single bond or a double bond; Ar1 represents a phenyl group which may be substituted with 1 to 3 substituents selected from Group A1 of Substituents, or a pyridinyl group which may be substituted with 1 to 3 substituents selected from Group A1 of Substituents; R1 and R2 are the same or different and each represent a hydrogen atom or a group selected from the following Group A1 of Substituents; Z1 represents a methylene group or vinyl group, which may be substituted with 1 or 2 substituents selected from Group A1 of Substituents, an oxygen atom, or an imino group that may be substituted with a substituent selected from Group A1 of Substituents; and p, q, and rs are the same or different and represent an integer from 0 to 2; Group A1 of Substituents: (1) a halogen atom, (2) a hydroxyl group, (3) a cyano group, (4) a C3-8 cycloalkyl group, (5) a C3-8 cycloalkoxy group, (6) a C1-6 alkyl group, in which the C1-6 alkyl group may be substituted with 1 to 3 substituents selected from the group which it consists of a halogen atom, hydroxyl group, cyano group, C3-8 cycloalkyl group, C1-6 alkoxy group, and C3-8 cycloalkoxy group, (7) a C1-6 alkoxy group, in which the group C1-6 alkoxy may be substituted with 1 to 3 substituents selected from the group consisting of a halogen atom, hydroxyl group, cyano group, C3-8 cycloalkyl group, and C3-8 cycloalkoxy group, (8) an amino group that it can be substituted with one or two C1-6 alkyl groups, in which the C1-6 alkyl groups can be substituted with 1 to 3 halogen atoms, (9) a carbamoyl group which can be r substituted with one or two C1-6 alkyl groups, in which the C1-6 alkyl group may be substituted with 1 to 3 halogen atoms, (10) a carboxyl group, (11) a C1-6 alkoxy group carbonyl, wherein the C1-6 alkoxy group may be substituted with 1 to 3 substituents selected from the group consisting of halogen atom, hydroxyl group, cyano group, C3-8 cycloalkyl group, and C3-8 cycloalkoxy group, (12) a C1-6 acyl group and (13) C1-6 alkyl sulfonyl group, with the proviso that the compounds of formula (I) are not (E) - (3S) - (4-fluorophenyl) -6 - [3-Methoxy-4- (4-methyl-1H-imidazol-1-yl) benzylidene] - (9R) -hexahydroindolizin-5-one, (E) - (3R) - (4-fluorophenyl) -6- [3-Methoxy-4- (4-methyl-1H-imidazol-1-yl) benzylidene] - (9S) -hexahydroindolizin-5-one, (E) - (3S) - (4-fluorophenyl) -6- [ 3-methoxy-4- (4-methyl-1H-imidazol-1-yl) benzylidene] - (9S) -hexahydroindolizin-5-one and (E) - (3R) - (4-fluorophenyl) -6- [3 -methoxy-4- (4-methyl-1H-imidazol-1-yl) benzylidene] - (9R) -hexahydroindolizin-5-one. |
| priorityDate | 2005-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 983.