http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2394180-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ccd9173f2aabd93562c916f9a2dbff4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9911f3ffb183144488431472d9039dfa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-40 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1774 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725 |
| filingDate | 2009-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2013-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d40300a8a287947c70dc671bb81213f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0528915efab6a8c8154ebdec375dd01f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a0e427480eb7b32ff56938daac9bb1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38e135eda3eecfb5c314d99cf4a41d02 |
| publicationDate | 2013-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2394180-T3 |
| titleOfInvention | High affinity and use of T-cell receptor |
| abstract | A nucleic acid molecule encoding the V (D) J regions of a TCR that recognizes tyrosinase and comprises the nucleic acid sequence SEQ ID No. 1 encoding the α chain and / or the acidic sequence SEQ ID NO. 2 encoding the ß chain of said TCR, or derivative thereof encoding the α or ß chains, where the chain has been altered by one or more additions or deletions of 1-15 amino acids, the additions or deletions being outside the CDR3 region of each chain and / or by conservative substitutions of 1-15 amino acids, in which the tyrosinase recognition characteristics are maintained or improved, or a fragment thereof that encodes a CDR3 region of a TCR that recognizes tyrosinase and has the sequence of nucleic acids of SEQ ID No. 3 or 4 or encoding the amino acid sequences of SEQ ID No. 5 or 6, or derivative of said fragment, in which the CDR3 region has been altered by one or more additions and / odelec ions of a total number of up to 1-5 amino acids, but not more than 1-3 contiguous amino acids, and / or conservative substitutions of up to 1-6 amino acids and in which the latirosinase recognition characteristics are maintained or improved. |
| priorityDate | 2008-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 187.