abstract |
Annexin A5 or functional analogue or variant thereof for use in the treatment of vascular dysfunction associated with altered endothelial-mediated vasodilation, a reduced endothelial nitric oxide synthase (eNOS) activity and / or a reduced nitric oxide (NO) bioavailability, the analogue or functional variant of annexin A5 comprising a protein that is more than 90% identical to human annexin A5, SEQ ID NO: 1. |