| abstract |
A compound having the formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 is hydrogen or alkyl; R2 is hydrogen, halogen, alkyl, haloalkyl, aryl, heteroaryl, cycloalkyl or heterocycle; R3 is cycloalkyl, aryl, heteroaryl , heterocycle, - (CRaRb) m-R4, -C (O) OR5, -C (R5)> = NO (RV), -C (O) -R5 or -C (O) -N (R5) (R6 ); m is 1, 2, 3 or 4; Ra, in each case, is independently hydrogen, halogen, alkyl, alkenyl, haloalkyl, -OR7a, -N (R8) (R9), - C (O) OR7b, - C (O) -R7b, -C (O) -N (R8) (R9), - (CRcRd) p-OR7a, - (CRcRd) pN (R8) (R9), - (CRcRd) pC (O) 0R7b , - (CRcRd) pC (O) -R7b, - (CRcRd) pC (O) -N (R8) (aryl, heteroaryl, cycloalkyl or heterocycle; Rb, in each case, is independently hydrogen, halogen, alkyl , alkenyl, haloalkyl, -C (O) OR7b, -C (O) -R7b, -C (O) -N (R8) (R9), - (CRcRd) p-OR7a, - (CRcRd) pN (R8) (R9), - (CRcRd) pC (O) OR7b, - (CRcRd) pC (O) -R7b, - (CRcRd) pC (O) -N (R8) (R9), aryl, heteroaryl, cycloalkyl or heterocycle. |