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filingDate 2007-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23ef113bb93d1aa9f85854abaa7000e4
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publicationDate 2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2390289-T3
titleOfInvention Synthetic platelets
abstract A synthetic platelet substitute that interacts with platelets and the (sub) endothelium, which comprises: a. a carrier molecule comprising lipid particles with a crosslinked surface mesh, in which the lipid particles comprise: an internal lipid particle of pharmaceutically acceptable departic forming lipids; hydrophilic polymer chains attached to the surface of the lipid particle, the hydrophilic polymer chains being non-toxic linear chain and comprising a cross-linkable terminal group at the free ends thereof; and crosslinking groups that join the end groups of the hydrophilic polymer chains to form the crosslinked surface mesh; and b. at least one receptor molecule bound to the surface of the carrier molecule, wherein the receptor molecule is a peptide selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4 , SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEC ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, SEQ ID NO: 19, SEQ ID NO: 20, SEQ ID NO: 21, SEQ ID NO: 22, analogs thereof having a sequence identity of 90% and modified peptides thereof having an insertion of a Cys residue and / or a spectrophotometrically traceable amino acid and / or a poly-Gly marker consisting of from 1 to 5 residues of Gly.
priorityDate 2006-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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