| abstract |
Immunogenic composition comprising at least one influenza antigen and an oil-in-water adjuvant emulsion obtained by a phase inversion process by varying the temperature of a mixture comprising at least: - squalene, - an aqueous solvent, - a polyoxyethylene alkyl ether , whose hydrophilic / lipophilic balance is greater than or equal to 10, - a hydrophobic nonionic surfactant, whose hydrophilic / lipophilic balance is interior or equal to 9. |