abstract |
A process for separating a mixture of alkyl ester enantiomers comprising contacting the mixture with an enzyme effective to preferably stimulate the hydrolysis of one of the enantiomers; characterized in that the contact is carried out in the presence of a buffer, in which the alkyl ester has the following formula: in which: R25 is an amino protecting group; and R26 is selected from the group consisting of C1-10 alkyl, C6-14 aryl, C7-16 alkylaryl, C3-7 cycloalkyl or C3-10 cycloalkyl alkyl. |