abstract |
A compound of Formula (I) ** Formula ** or a therapeutically acceptable salt thereof, where R1, R2 and R3 are independently selected from the group consisting of hydrogen and halogen; Ar1 is aryl, where Ar1 is eventually substituted with halogen; X1 it is alkylenyl: Z is heterocycle, where Z is substituted with 1, 2, 3 or 4 substituents selected from the group consisting of alkoxyalkyl, haloalkyl, hydroxyalkyl, NRCRD and NRCRDalkyl; yRC and RD are independently selected from the group consisting of hydrogen, alkyl, cycloalkyl and cycloalkylalkyl, provided that, when Z is a 5 or 6-membered non-aromatic ring containing 1 or 2 nitrogen atoms and possibly a sulfur or oxygen atom , then Z is not attached to X1 through a carbon atom. |