| abstract |
Links of 3'-deoxyipentopyranosyl nucleosides of the formula (I), in which R1 is equal to OH, Hal with Hal equal to Br or Cl, a radical chosen from between i-Pr equal to isopropyl, or -O-PH - (> = O) (- O '), R2, R3 and R4, independently of each other, equal or different, mean in each case H, NR5R6, OR7, SR8,> = O, CnH2n + 1 where n is an integer from 1-12, preferably 1-8, in particular 1-4, a group removable in the β position of the formula -OCH2CH2R18 with R18 equal to cyano or a p-nitrophenyl radical or a fluorenylmethyloxycarbonyl radical (Fmoc), or (CnH2n) NR10R11, with R10R11 equal to H, CnH2n + 1 or R10R11 linked through a radical of the formula in which R12, R13, R14 and R15, independently of each other, equal or different, mean in each case H, OR7, or CnH2n + 1 or CnH2n-1, having n the above-mentioned meaning, and in which R5, R6, R7 and R8 independently of each other, equal or different, mean in each case H, CnH2n + 1 or CnH2n-1 , having n the meaning Above mentioned, - (CO) R9 with R9 equal to a linear or branched alkyl radical, optionally substituted, aryl, preferably phenyl. |