abstract |
The present invention is a compound derived from pyrimidine urea for the treatment of inflammatory diseases. The compound of the invention is useful for the preparation of a pharmaceutical composition for the treatment of said inflammatory diseases, preferably, sepsis caused by Gram-negative bacteria, arthritis, kidney infections, acute pulmonary diseases induced by sepsis, induced acute respiratory distress syndrome. by sepsis, endotoxic shock or endotoxemia, septic peritonitis, acute hepatitis, acute myocardial dysfunction induced by septic shock and necrotizing enterecolitis. |