http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2383908-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65744 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-09 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 |
| filingDate | 2006-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0eaf7678ae282b1748dea12a2153527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4122560503e1fc1d9ae7cb4c6ace947a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bdc0eb47fbb911d960a8e32a2336794 |
| publicationDate | 2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2383908-T3 |
| titleOfInvention | Process for preparing (alpha S, beta R) -6-bromo-alpha- [2- (dimethylamino) ethyl] -2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinolineethanol |
| abstract | A process for isolating (αS, βR) -6-bromo-α- [2- (dimethylamino) ethyl] -2-methoxy-α-1-naphthalenyl-β-phenyl-3quinolineethanol from a mixture of 6- stereoisomeric forms bromo-α- [2- (dimethylamino) ethyl] -2-methoxy-α-1 naphthalenyl-β-phenyl-3-quinolineethanol by optical resolution with 4-hydroxy 4-oxide oxide [2,1-d: 1 ' , 2'f] [1, 3, 2] chiral dioxaphosphepine or a derivative thereof as a resolution agent, said process comprising a) reacting a mixture of stereoisomeric forms of 6-bromo-α- [2- (dimethylamino) ethyl ] -2-Methoxy-α-1naphthalenyl-β-phenyl-3-quinolineethanol with said resolution agent in a suitable solvent; b) separating the resulting crystallized salt from (αS, βR) -6-bromo-α- [2- (dimethylamino) ethyl] -2-methoxy-α-1-naphthalenyl-β-phenyl-3quinolineethanol and said resolution agent of the reaction mixture obtained in a); c) optionally recrystallize or suspend the salt obtained in b) in a suitable solvent; d) release the (αS, βR) -6-bromo-α- [2- (dimethylamino) ethyl] -2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol salt obtained in b) oc ). |
| priorityDate | 2005-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.