http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2383900-T3
Outgoing Links
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67dd1f39f37bac4617e37d6d5c60aa8b |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
filingDate | 2005-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c28fc08fefc6fa09249f9bddb0aba19b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aff5800d7878412d3ba6b55ed8360b35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5e4669472162ca66cef3add699284c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_596380702774530b07ca7cd175980a56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dda02fea3f835e7fe92bc87b8b9a5f72 |
publicationDate | 2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2383900-T3 |
titleOfInvention | Tetrahydroquinoline derivatives and a procedure for their preparation |
abstract | A compound of formula (I): wherein R 1 is a hydrogen atom, an optionally substituted alkoxycarbonyl group, an optionally substituted carbamoyl group, an optionally substituted alkyl group, an optionally substituted alkanoyl group, a saturated or unsaturated monocyclic or bicyclic heterocyclic group containing 1 to 4 heteroatoms independently selected from oxygen, sulfur and nitrogen atoms (the heterocyclic group is optionally substituted), or a saturated or unsaturated monocyclic or bicyclic heterocyclic carbonyl group containing 1 to 4 heteroatoms independently selected from oxygen, sulfur atoms and nitrogen (the heterocyclic group is optionally substituted); R2 is a hydrogen atom or an optionally substituted alkyl group; R3 is a hydrogen atom or an optionally substituted alkyl group; R4 is an optionally substituted alkylene group; R5 is a saturated or unsaturated monocyclic or bicyclic heterocyclic group containing 1 to 4 heteroatoms independently selected from oxygen, sulfur and nitrogen atoms, where the heterocyclic group is substituted with 1 to 5 substituents selected from the following groups, or said heterocyclic group it is substituted with 1 to 5 substituents selected from the following groups and additionally with a halogen atom, an oxo and / or hydroxy group: a cyano group, a nitro group, a carboxyl group, a sulfo group, a C3-C10 alkyl group , a substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted alkenyl group, a C3-C10 alkoxy group, a substituted alkoxy group, an optionally substituted cycloalkoxy group, an optionally substituted alkoxycarbonyl group, an optionally substituted carbamoyl group, an optionally substituted carbamoyl group optionally substituted carbamimidoyl, an optionally substituted alkylthio group, a optionally substituted alkylsulfinyl group, an optionally substituted alkylsulfonyl group, an optionally substituted amino group, an optionally substituted sulfamoyl group, an optionally substituted alkanoyl group, a saturated or unsaturated monocyclic or bicyclic heterocyclic group containing 1 to 4 heteroatoms independently selected from atoms of oxygen, sulfur and nitrogen (the heterocyclic group is optionally substituted), a saturated or unsaturated monocyclic or bicyclic heterocycle-oxy group containing 1 to 4 heteroatoms independently selected from oxygen, sulfur and nitrogen atoms (the heterocycle-oxy group is optionally substituted ), and a saturated or unsaturated monocyclic or bicyclic heterocyclic carbonyl group containing 1 to 4 heteroatoms independently selected from oxygen, sulfur and nitrogen atoms (the heterocyclic carbonyl group is optionally substituted); R6, R7, R8 and R9 are independently a hydrogen atom, a halogen atom, a hydroxy group, a nitro group, a cyano group, an optionally substituted alkyl group, an optionally substituted alkoxy group, an optionally substituted alkylsulfonyloxy group or a optionally substituted amino group, oR6 and R7, or R7 and R8, or R8 and R9 can be combined at the ends to form an alkylene group whose alkylene group may contain 1 to 3 heteroatoms independently selected from nitrogen, sulfur and oxygen atoms, and may have one or more substituents, and R10 is an aromatic ring optionally containing 1 to 3 heteroatoms independently selected from oxygen, sulfur and nitrogen atoms (the aromatic ring is optionally substituted), or a pharmaceutically acceptable salt thereof. |
priorityDate | 2004-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 820.