abstract |
An injectable immunogenic composition comprising capsular saccharides of serogroups A, C, W135 and Y of Neisseria meningitidis, in which: (i) said capsular saccharides are conjugated to a carrier protein to give individual conjugates for each of the four serogroups; (ii) the conjugates have a ratio of saccharide: protein (w / w) with an excess of protein; and (iii) the composition contains between 10 μg and 25 μg of meningococcal capsular saccharides per dose, with an amount of 2.5 μg, 5 μg or 10 μg of each saccharide. |