| abstract |
Isolated monoclonal antibody that binds to a human Toll 4 (TLR4) / MD-2 type receptor complex, inhibiting the monoclonal antibody at least 50% of the production of IL-8 induced by lipopolysaccharide (LPS) in a solution comprising HEK293 cells transfected with human TLR4 / MD-2 when said monoclonal antibody is added to said solution at a concentration of 10 μg / ml, compared to the level of IL-8 production induced by LPS in the absence of said monoclonal antibody. |