Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a70b05f3bdf7f6e9aaf7a41ac3aacdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
filingDate |
2004-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7015cfcc0f9cb90c3e4e112053469aa3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3ce166104884cfd72a3c421673fbf98 |
publicationDate |
2012-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2382035-T3 |
titleOfInvention |
Procedure to modify the formation of sodium mycophenolate drug crystals |
abstract |
Method for modifying the crystalline habit of an acicular drug crystal, in which the acicular pharmacological substance is a mycophenolate sodium salt, which comprises suspending said crystalline pharmacological substance in a methanol / water solvent system in a ratio ranging from 98: 2 and 90:10, and subjecting said suspension to a temperature oscillation, in which the crystalline habit is modified because the average aspect ratio of the processed crystals is less than 10: 1 and the apparent density is greater than 200 kg / m3 |
priorityDate |
2003-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |