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publicationDate 2012-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2382035-T3
titleOfInvention Procedure to modify the formation of sodium mycophenolate drug crystals
abstract Method for modifying the crystalline habit of an acicular drug crystal, in which the acicular pharmacological substance is a mycophenolate sodium salt, which comprises suspending said crystalline pharmacological substance in a methanol / water solvent system in a ratio ranging from 98: 2 and 90:10, and subjecting said suspension to a temperature oscillation, in which the crystalline habit is modified because the average aspect ratio of the processed crystals is less than 10: 1 and the apparent density is greater than 200 kg / m3
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